Description
Thymosin Alpha-1 (Tα1) is a synthetic version of a naturally occurring thymic peptide involved in immune system regulation. It is a 28–amino acid, N-terminally acetylated peptide that has been extensively studied in immunology and cellular signaling research due to its role in modulating innate and adaptive immune responses.
Thymosin Alpha-1 has been investigated for its effects on T-cell maturation, dendritic cell activity, cytokine signaling, and immune homeostasis. Research frequently focuses on its interaction with pathways related to immune surveillance, inflammation control, and host defense mechanisms, making it a common subject in studies involving viral response models, oncology-related immune signaling, and autoimmune research frameworks.
Name: Thymosin Alpha-1
Type: Synthetic peptide (endogenous thymic peptide analog)
Molecular Formula: C₁₂₉H₂₁₅N₃₃O₅₅
Molecular Weight: ≈ 3,108.3 Da
CAS Number: 62304-98-7
Sequence: Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN
(28 amino acids, N-terminally acetylated)
Structure Type: Linear peptide (non-cyclic, predominantly α-helical regions in solution)






