Description

TB-500 (Thymosin Beta-4) is a synthetic version of a naturally occurring peptide found in high concentrations in human platelets and tissues. It is best known in research settings for its role in cell migration, tissue repair, and actin regulation. TB-500 interacts with G-actin, helping regulate cytoskeletal organization, which is a foundational process in wound healing and cellular movement.

TB-500 has been studied for its involvement in soft tissue recovery, angiogenesis (formation of new blood vessels), inflammation modulation, and cellular survival pathways. These properties have made it a frequent subject of investigation in musculoskeletal, cardiovascular, and regenerative biology research models.

Name: TB-500 (Thymosin Beta-4)

Type: Synthetic peptide (naturally occurring endogenous peptide analog)

Molecular Formula: C₂₁₂H₃₅₀N₅₆O₇₈S

Molecular Weight: ≈ 4,963.4 Da

CAS Number: 77591-33-4

Sequence: Ac-SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES

(43 amino acids, N-terminally acetylated)

Structure Type: Linear polypeptide (non-cyclic, unstructured peptide)